Compile Data Set for Download or QSAR
maximum 50k data
Found 19 of ic50 data for polymerid = 50004089
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50536679(CHEMBL4568087)
Affinity DataIC50:  48nMAssay Description:Inhibition of full-length recombinant human GST-tagged NEK4 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50265242(3-(4-(4-iodophenoxy)thieno[2,3-c]pyridin-2-yl)-1,2...)
Affinity DataIC50:  50nMAssay Description:Inhibition of NEK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  74.2nMAssay Description:Inhibition of human NEK4 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50613381(CHEMBL5278787)
Affinity DataIC50:  80nMAssay Description:Inhibition of NEK4 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  96nMAssay Description:Inhibition of human NEK4 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50536675(CHEMBL4569508)
Affinity DataIC50:  160nMAssay Description:Inhibition of full-length recombinant human GST-tagged NEK4 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50381716(ABT-348 | ILORASERTIB | US8722890, 1 | US8722890, ...)
Affinity DataIC50:  200nMAssay Description:Inhibition of NEK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50536678(CHEMBL4550702)
Affinity DataIC50:  240nMAssay Description:Inhibition of full-length recombinant human GST-tagged NEK4 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50613379(CHEMBL1994830)
Affinity DataIC50:  316nMAssay Description:Inhibition of NEK4 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50536681(CHEMBL4552628)
Affinity DataIC50:  480nMAssay Description:Inhibition of full-length recombinant human GST-tagged NEK4 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50613380(CHEMBL1988153)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of NEK4 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50613378(CHEMBL1997822)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of NEK4 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50396534(CHEMBL2171124)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of NEK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM121388(US8722890, 3)
Affinity DataIC50: >3.90E+3nMAssay Description:Inhibition of NEK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full-length human NEK4 P225A mutant using myelin basic protein as substrate measured after 40 mins in presence of [gamma33P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50499634(CHEMBL3741589)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NEK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged NEK4 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NEK4 using MBP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant full length human GST-tagged NEK4 expressed in baculovirus expression system using serine/threonine-7 peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed